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MCM3 Rabbit pAb
db143
Datasheet
- Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Immunogen A synthetic peptide of human MCM3
-
Gene ID
4172
-
Swiss Prot
P25205
- Synonyms HCC5; P1.h; RLFB; P1-MCM3
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC
-
Recommended dilution
WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:20-1:50
FC: 1:20 - Calculated MW 91 kDa
- Observed MW 100 kDa
- Host species Rabbit
- Clonality Polyclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 20μL 598
- 50μL 998
- 100μL 1798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
