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HDAC3 Recombinant Rabbit mAb
db14165
Datasheet
- Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human HDAC3
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Gene ID
8841
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Swiss Prot
O15379
- Synonyms HD3; RPD3; RPD3-2
- Reactivity Human, Mouse, Rat
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:50
ICC/IF: 1:200-1:500
FC: 1:20
IP: 1:20-1:50 - Calculated MW 49 kDa
- Observed MW 49 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of HDAC3 in 3T3,Hela,Rat Brain cell lysates using HDAC3 antibody(1:1000 diluted). -
Western blot analysis of extracts from A431 cells using db14165 at 1:3000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
