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Phospho-p53 (Ser392) Recombinant Rabbit mAb
db14129
Datasheet
- Background This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser392 of human p53
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Gene ID
7157
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Swiss Prot
P04637
- Synonyms P53; BCC7; LFS1; TRP53
- Reactivity Human
- Application WB, IHC, ICC/IF, IP
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Recommended dilution
WB: 1:2000
IHC: 1:100
ICC/IF: 1:100
IP: 1:20 - Calculated MW 44 kDa
- Observed MW 53 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from 293 cells using db14129 at 1:1000. -
Western blot analysis of extracts from SW620 cells using db14129 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
