CDC42 Recombinant Rabbit mAb - diagbio | 戴格生物

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CDC42 Recombinant Rabbit mAb

db14118

Product Name : CDC42 Recombinant Rabbit mAb

Cat.No.: db14118

Synonyms : TKS; G25K; CDC42Hs

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Immunogen Recombinant protein of human CDC42
Gene ID 998
Swiss Prot P60953
Synonyms TKS; G25K; CDC42Hs
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:20000
IHC: 1:100-1:200
ICC/IF: 1:200-1:500
FC: 1:100
IP: 1:20
Calculated MW 21 kDa
Observed MW 21 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of CDC42 in C6,Hela cell lysates using CDC42 antibody(1:1000 diluted).

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