SIRT1 (DGR18233) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

SIRT1 (DGR18233) Rabbit mAb

db14034

Datasheet

Product Name : SIRT1 (DGR18233) Rabbit mAb

Cat.No.: db14034

Synonyms : SIR2; SIR2L1; SIR2alpha

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Immunogen Recombinant protein of human SIRT1
Gene ID 23411
Swiss Prot Q923E4
Synonyms SIR2; SIR2L1; SIR2alpha
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
ICC/IF: 1:100
FC: 1:50-1:100
IP: 1:20-1:50
Calculated MW 82 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR18233
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of SIRT1 in K562,C6,3T3,Hela cell lysates using SIRT1 antibody(1:1000 diluted).
Western blot analysis of extracts from Rat pancreas tissus using db14034 at 1:1000.

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