Phospho-SHP2 (Tyr542) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-SHP2 (Tyr542) Recombinant Rabbit mAb

db13976

Product Name : Phospho-SHP2 (Tyr542) Recombinant Rabbit mAb

Cat.No.: db13976

Synonyms : CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3

Application : WB, ICC/IF, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr542 of human SHP2
Gene ID 5781
Swiss Prot Q06124
Synonyms CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3
Reactivity Human, Mouse
Application WB, ICC/IF, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:100-1:200
IP: 1:20
Calculated MW 68 kDa
Observed MW 68 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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