产品中心 Products Center
Phospho-RPS6 (Ser240/Ser244) Recombinant Rabbit mAb
db13958
Datasheet

Product Name : Phospho-RPS6 (Ser240/Ser244) Recombinant Rabbit mAb

Cat.No.: db13958

Synonyms : S6

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
  • Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser240/Ser244 of human RPS6
  • Gene ID 6194
  • Swiss Prot P62753
  • Synonyms S6
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, ICC/IF, FC, IP
  • Recommended dilution WB: 1:1000-1:5000
    IHC: 1:200-1:1000
    ICC/IF: 1:100
    FC: 1:500
    IP: 1:20
  • Calculated MW 29 kDa
  • Observed MW 32 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.