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beta Catenin (DGR12883) Rabbit mAb
db13925
Datasheet
- Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
- Immunogen A synthetic peptide of human beta Catenin
-
Gene ID
1499
-
Swiss Prot
P35222
- Synonyms EVR7; CTNNB; MRD19; armadillo
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:100-1:200
IP: 1:20-1:50 - Calculated MW 86 kDa
- Observed MW 86 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR12883
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of beta Catenin in C6,CHO-K1,Hela cell lysates using beta Catenin antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human Cholangiocarcinoma using db13925 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
