Phospho-ULK1 (Ser467) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-ULK1 (Ser467) Recombinant Rabbit mAb

db13918

Product Name : Phospho-ULK1 (Ser467) Recombinant Rabbit mAb

Cat.No.: db13918

Synonyms : ATG1; ATG1A; UNC51; hATG1; Unc51.1

Application : WB

Reactivity : Human

Host species : Rabbit

Background Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR.
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser467 of human ULK1
Gene ID 8408
Swiss Prot O75385
Synonyms ATG1; ATG1A; UNC51; hATG1; Unc51.1
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 113 kDa
Observed MW 130 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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