GAB2 (DGR31903) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

GAB2 (DGR31903) Rabbit mAb

db13625

Datasheet

Product Name : GAB2 (DGR31903) Rabbit mAb

Cat.No.: db13625

Synonyms : KIAA0571; GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100

Application : WB

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Immunogen A synthetic peptide of human GAB2
Gene ID 9846
Swiss Prot Q9UQC2
Synonyms KIAA0571; GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100
Reactivity Human,Mouse,Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 75 kDa
Observed MW 98 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR31903
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from K562 cells using db13625 at 1:1000.
Western blot analysis of extracts from Mouse heart tissue using db13625 at 1:1000.

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