PRMT1 (DGR20915) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

PRMT1 (DGR20915) Rabbit mAb

db13579

Datasheet

Product Name : PRMT1 (DGR20915) Rabbit mAb

Cat.No.: db13579

Synonyms : ANM1; HCP1; IR1B4; HRMT1L2

Application : WB, IHC-P

Reactivity : Human,Mouse

Host species : Rabbit

Background This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
Immunogen A synthetic peptide of human PRMT1
Gene ID 3276
Swiss Prot Q99873
Synonyms ANM1; HCP1; IR1B4; HRMT1L2
Reactivity Human,Mouse
Application WB, IHC-P
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:100-1:200
Calculated MW 43 kDa
Observed MW 43 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR20915
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of PRMT1 in K562,C6 cell lysates using PRMT1 antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human breast cancer using db13579 antibody.

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