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Mre11 Recombinant Rabbit mAb
db13499
Datasheet
- Background This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human Mre11
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Gene ID
4361
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Swiss Prot
P49959
- Synonyms ATLD; HNGS1; MRE11A; MRE11B
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, FC
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Recommended dilution
WB: 1:1000
IHC-P: 1:200-1:2000
FC: 1:200-1:500 - Calculated MW 81 kDa
- Observed MW 81 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Mre11 in K562,Rat Brain,C6,3T3,Hela cell lysates using Mre11 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human lung cancer using db13499 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
