Rad51 Recombinant Rabbit mAb - diagbio | 戴格生物

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Rad51 Recombinant Rabbit mAb

db13496

Product Name : Rad51 Recombinant Rabbit mAb

Cat.No.: db13496

Synonyms : RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930

Application : IHC, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Immunogen A synthetic peptide of human Rad51
Gene ID 5888
Swiss Prot Q06609
Synonyms RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930
Reactivity Human
Application IHC, ICC/IF, FC
Recommended dilution IHC: 1:50
ICC/IF: 1:20
FC: 1:50
Calculated MW 37 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Rad51 in A549,HL-60,U2OS cell lysates using Rad51 antibody(1:1000 diluted).

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