Phospho-YAP1 (Ser127) (DGR19954) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Phospho-YAP1 (Ser127) (DGR19954) Rabbit mAb

db13334

Datasheet

Product Name : Phospho-YAP1 (Ser127) (DGR19954) Rabbit mAb

Cat.No.: db13334

Synonyms : YAP; YKI; COB1; YAP2; YAP65

Application : WB, IHC-P

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1
Gene ID 10413
Swiss Prot P46937
Synonyms YAP; YKI; COB1; YAP2; YAP65
Reactivity Human,Mouse,Rat
Application WB, IHC-P
Recommended dilution WB: 1:2000-1:20000
IHC-P: 1:100-1:200
Calculated MW 55 kDa
Observed MW 70-75 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR19954
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-YAP1 (Ser127) in Hela,Hela+CalyculinA using Phospho-YAP1 (Ser127) antibody.
Western blot analysis of extracts from T24 cells and Rat spleen，Mouse muscle tissue using db13334 at 1:6000.

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