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BACE1 Recombinant Rabbit mAb
db13283
Datasheet
- Background This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality. [provided by RefSeq, Nov 2015]
- Immunogen Recombinant protein of mouse BACE1
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Gene ID
23821
-
Swiss Prot
P56818
- Synonyms ASP2; Bace; C76936
- Reactivity Mouse, Rat
- Application WB, IHC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:50
IP: 1:20 - Calculated MW 56 kDa
- Observed MW 70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of BACE1 in Rat Brain lysates using BACE1 antibody(1:1000 diluted). -
Western blot analysis of extracts from Mouse brain tissue using db13283 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
