BACE1 (DGR16149) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

BACE1 (DGR16149) Rabbit mAb

db13283

Datasheet

Product Name : BACE1 (DGR16149) Rabbit mAb

Cat.No.: db13283

Synonyms : ASP2; Bace; C76936

Application : WB, IHC-P, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality. [provided by RefSeq, Nov 2015]
Immunogen Recombinant protein of mouse BACE1
Gene ID 23821
Swiss Prot P56818
Synonyms ASP2; Bace; C76936
Reactivity Human,Mouse,Rat
Application WB, IHC-P, IP
Recommended dilution WB: 1:1000
IHC-P: 1:50
IP: 1:50
Calculated MW 56 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR16149
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of BACE1 in Rat Brain lysates using BACE1 antibody(1:1000 diluted).
Western blot analysis of extracts from Mouse brain tissue using db13283 at 1:1000.

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