Ras (DGR13636) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Ras (DGR13636) Rabbit mAb

db13171

Datasheet

Product Name : Ras (DGR13636) Rabbit mAb

Cat.No.: db13171

Synonyms : NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
Immunogen A synthetic peptide of human Ras
Gene ID 4893
Swiss Prot P01111
Synonyms NS6; CMNS; NCMS; ALPS4; N-ras; NRAS1
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:500-1:2000
ICC/IF: 1:50-1:100
FC: 1:20-1:50
IP: 1:10-1:100
Calculated MW 22 kDa
Observed MW 22 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR13636
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Ras in Hela,3T3,C6,Rat Brain,MCF7 cell lysates using Ras antibody(1:1000 diluted).
Western blot analysis of extracts from 293 cells using db13174 at 1:1000.

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