p27 KIP 1 Recombinant Rabbit mAb - diagbio | 戴格生物

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p27 KIP 1 Recombinant Rabbit mAb

db13072

Product Name : p27 KIP 1 Recombinant Rabbit mAb

Cat.No.: db13072

Synonyms : KIP1; MEN4; CDKN4; MEN1B; P27KIP1

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
Immunogen A synthetic peptide of human p27 KIP 1
Gene ID 1027
Swiss Prot P46527
Synonyms KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:50-1:100
ICC/IF: 1:100-1:500
FC: 1:50
IP: 1:20
Calculated MW 22 kDa
Observed MW 27 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of p27 KIP 1 in 3T3,Hela cell lysates using p27 KIP 1 antibody(1:1000 diluted).

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