BackgroundThe protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]
ImmunogenRecombinant protein of human KAT7/Hbo1/MYST2
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of KAT7/Hbo1/MYST2 in Hela,A549,MCF-7,293T cell lysates using KAT7/Hbo1/MYST2 antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using db13014 antibody.
Immunofluorescent analysis of HCT116 cells using db13014 antibody (green), and DAPI (blue).