BMP4 (DGR15418) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

BMP4 (DGR15418) Rabbit mAb

db12985

Datasheet

Product Name : BMP4 (DGR15418) Rabbit mAb

Cat.No.: db12985

Synonyms : ZYME; BMP2B; OFC11; BMP2B1; MCOPS6

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Immunogen A synthetic peptide of human BMP4
Gene ID 652
Swiss Prot P12644
Synonyms ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
Reactivity Human
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:20000
IHC-P: 1:100-1:200
ICC/IF: 1:200-1:500
FC: 1:100-1:500
IP: 1:10-1:100
Calculated MW 47 kDa
Observed MW 47 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR15418
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of BMP4 in K562,Hela cell lysates using BMP4 antibody(1:500 diluted).
Western blot analysis of extracts from HepG2 cells using db12985 at 1:5000.
Immunofluorescent analysis of HepG2 cells using db12985 antibody (green), and DAPI (blue).

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