Rel B Recombinant Rabbit mAb - diagbio | 戴格生物

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Rel B Recombinant Rabbit mAb

db12863

Product Name : Rel B Recombinant Rabbit mAb

Cat.No.: db12863

Synonyms : IREL; I-REL; IMD53; REL-B

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
Immunogen A synthetic peptide of human Rel B
Gene ID 5971
Swiss Prot Q01201
Synonyms IREL; I-REL; IMD53; REL-B
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20-1:100
FC: 1:20
IP: 1:20
Calculated MW 62 kDa
Observed MW 62 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from HeLa，MCF-7 cells using db12863 at 1:1000.

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