XRCC1 Recombinant Rabbit mAb - diagbio | 戴格生物

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XRCC1 Recombinant Rabbit mAb

db12821

Product Name : XRCC1 Recombinant Rabbit mAb

Cat.No.: db12821

Synonyms : RCC; SCAR26

Application : WB, IHC, ICC/IF

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human XRCC1
Gene ID 7515
Swiss Prot P18887
Synonyms RCC; SCAR26
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
Calculated MW 70 kDa
Observed MW 82 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of XRCC1 in A549,MCF-7,293T cell lysates using XRCC1 antibody(1:1000 diluted).

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