Caspase-10 (DGR14068) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Caspase-10 (DGR14068) Rabbit mAb

db12792

Datasheet

Product Name : Caspase-10 (DGR14068) Rabbit mAb

Cat.No.: db12792

Synonyms : MCH4; ALPS2; FLICE2

Application : WB, IHC-P, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
Immunogen Recombinant protein of human Caspase-10
Gene ID 843
Swiss Prot Q92851
Synonyms MCH4; ALPS2; FLICE2
Reactivity Human
Application WB, IHC-P, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:50-1:100
FC: 1:100-1:500
IP: 1:10-1:100
Calculated MW 59 kDa
Observed MW 59 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14068
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Caspase 10 in K562 cell lysates using Caspase 10 antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human lung cancer using db12792 antibody.

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