Neurofilament heavy polypeptide (DGR14226) Rabbit mAb - diagbio

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Recombinant DGRmAb^®

Neurofilament heavy polypeptide (DGR14226) Rabbit mAb

db12729

Datasheet

Product Name : Neurofilament heavy polypeptide (DGR14226) Rabbit mAb

Cat.No.: db12729

Synonyms : NFH; CMT2CC

Application : WB, IHC-P, ICC/IF

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Immunogen Recombinant protein of human Neurofilament heavy polypeptide
Gene ID 4744
Swiss Prot P12036
Synonyms NFH; CMT2CC
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:1000
ICC/IF: 1:100
Calculated MW 113 kDa
Observed MW 180-220 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR14226
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Neurofilament heavy polypeptide in mouse brain using Neurofilament heavy polypeptide antibody.

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