您当前的位置：
JNK1/JNK2/JNK3 Recombinant Rabbit mAb
db12713
Datasheet
- Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
- Immunogen Recombinant protein of human JNK1
-
Gene ID
5599
-
Swiss Prot
P45983
- Synonyms JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
- Reactivity Human, Mouse, Rat
- Application WB, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:1000
ICC/IF: 1:200
FC: 1:100-1:200
IP: 1:50 - Calculated MW 48,53 kDa
- Observed MW 46,54 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
Western blot detection of JNK1/JNK2/JNK3 in C6,3T3 cell lysates using JNK1/JNK2/JNK3 antibody(1:1000 diluted).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
