Phospho-beta Catenin (Ser37) Recombinant Rabbit mAb - diagbio

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Phospho-beta Catenin (Ser37) Recombinant Rabbit mAb

db12691

Product Name : Phospho-beta Catenin (Ser37) Recombinant Rabbit mAb

Cat.No.: db12691

Synonyms : EVR7; CTNNB; MRD19; NEDSDV; armadillo

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser37 of human beta Catenin
Gene ID 1499
Swiss Prot P35222
Synonyms EVR7; CTNNB; MRD19; NEDSDV; armadillo
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 86 kDa
Observed MW 86 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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