Phospho-Alpha-synuclein (Tyr125) Recombinant Rabbit mAb - diagbio

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Phospho-Alpha-synuclein (Tyr125) Recombinant Rabbit mAb

db12656

Datasheet

Product Name : Phospho-Alpha-synuclein (Tyr125) Recombinant Rabbit mAb

Cat.No.: db12656

Synonyms : PD1; NACP; PARK1; PARK4

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr125 of human Alpha-synuclein
Gene ID 6622
Swiss Prot P37840
Synonyms PD1; NACP; PARK1; PARK4
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:50
Calculated MW 14 kDa
Observed MW 16 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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