Phospho-Bad (Ser112) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-Bad (Ser112) Recombinant Rabbit mAb

db12648

Product Name : Phospho-Bad (Ser112) Recombinant Rabbit mAb

Cat.No.: db12648

Synonyms : BBC2; BCL2L8

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser112 of human Bad
Gene ID 572
Swiss Prot Q92934
Synonyms BBC2; BCL2L8
Reactivity Human, Mouse, Rat
Application WB, IP
Recommended dilution WB: 1:2000
IP: 1:20
Calculated MW 18 kDa
Observed MW 23 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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