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Phospho-Bad (Ser112) (DGR32836) Rabbit mAb
db12648
Datasheet
- Background The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser112 of human Bad
-
Gene ID
572
-
Swiss Prot
Q92934
- Synonyms BBC2; BCL2L8
- Reactivity Human,Mouse,Rat
- Application WB, IP
-
Recommended dilution
WB: 1:1000-1:5000
IP: 1:20-1:50 - Calculated MW 18 kDa
- Observed MW 23 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32836
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
