ATF2 Recombinant Rabbit mAb - diagbio | 戴格生物

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ATF2 Recombinant Rabbit mAb

db12625

Product Name : ATF2 Recombinant Rabbit mAb

Cat.No.: db12625

Synonyms : HB16; CREB2; TREB7; CREB-2; CRE-BP1

Application : WB, IHC, ICC/IF, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Immunogen A synthetic peptide of human ATF2
Gene ID 1386
Swiss Prot P15336
Synonyms HB16; CREB2; TREB7; CREB-2; CRE-BP1
Reactivity Human
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:2000
IHC: 1:20
ICC/IF: 1:50
IP: 1:20
Calculated MW 55 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of ATF2 in Jurkat cell lysates using ATF2 antibody(1:500 diluted).
Western blot analysis of extracts from HepG2 cells using db12625 at 1:2000.

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