Phospho-p53 (Ser392) Recombinant Rabbit mAb
Product Name :
Phospho-p53 (Ser392) Recombinant Rabbit mAb
Cat.No.:
db12599
Synonyms :
P53; BCC7; LFS1; TRP53
Application :
WB, IHC, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Ser392 of human p53
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Gene ID
7157
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Swiss Prot
P04637
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Synonyms
P53; BCC7; LFS1; TRP53
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:100-1:200
IP: 1:20
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Calculated MW
44 kDa
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Observed MW
53 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from HEK293 cells using db12599 at 1:1000.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.