MBD3 Recombinant Rabbit mAb - diagbio | 戴格生物

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MBD3 Recombinant Rabbit mAb

db12550

Product Name : MBD3 Recombinant Rabbit mAb

Cat.No.: db12550

Synonyms : Methyl-CpG-binding protein MBD3

Application : WB, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Immunogen A synthetic peptide of human MBD3
Gene ID 53615
Swiss Prot O95983
Synonyms Methyl-CpG-binding protein MBD3
Reactivity Human, Mouse, Rat
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Calculated MW 33 kDa
Observed MW 33 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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