Caspase-6 Recombinant Rabbit mAb - diagbio | 戴格生物

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Caspase-6 Recombinant Rabbit mAb

db12533

Product Name : Caspase-6 Recombinant Rabbit mAb

Cat.No.: db12533

Synonyms : MCH2

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015]
Immunogen A synthetic peptide of human Caspase-6
Gene ID 839
Swiss Prot P55212
Synonyms MCH2
Reactivity Human, Mouse
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
Calculated MW 33 kDa
Observed MW 11kDa(cleavage),33 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Caspase-6 in A549,MCF-7,U251,HL-60 cell lysates using Caspase-6 antibody(1:1000 diluted).

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