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CD146 Recombinant Rabbit mAb
db12516
Datasheet
- Background Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
- Immunogen A synthetic peptide of human CD146
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Gene ID
4162
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Swiss Prot
P43121
- Synonyms CD146; MUC18
- Reactivity Human
- Application WB, ICC/IF
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Recommended dilution
WB: 1:2000
ICC/IF: 1:50 - Calculated MW 72 kDa
- Observed MW 120 kDa
- Host species Rabbit
- Clonality Monoclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot analysis of extracts from A375 cells using db12516 at 1:1000.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
