S6K1 (DGR12050) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

S6K1 (DGR12050) Rabbit mAb

db12507

Datasheet

Product Name : S6K1 (DGR12050) Rabbit mAb

Cat.No.: db12507

Synonyms : S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Immunogen A synthetic peptide of human S6K1
Gene ID 6198
Swiss Prot P23443
Synonyms S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:200-1:500
FC: 1:100-1:2000
IP: 1:100
Calculated MW 59 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR12050
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of S6K1 in Rat Brain lysates using S6K1 antibody(1:1000 diluted).
Western blot analysis of extracts from T24 cells using db12507 at 1:1000.
Immunofluorescent analysis of HeLa cells using db12507 antibody (green), and DAPI (blue).

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