NFkB p100 Recombinant Rabbit mAb - diagbio | 戴格生物

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NFkB p100 Recombinant Rabbit mAb

db12500

Product Name : NFkB p100 Recombinant Rabbit mAb

Cat.No.: db12500

Synonyms : p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100

Application : WB, ICC/IF, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Immunogen A synthetic peptide of human NFkB p100/NFKB2
Gene ID 4791
Swiss Prot Q00653
Synonyms p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100
Reactivity Human, Mouse
Application WB, ICC/IF, IP
Recommended dilution WB: 1:2000-1:10000
ICC/IF: 1:50
IP: 1:20
Calculated MW 97 kDa
Observed MW 120 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of NFKB p100 in K562, HeLa cell lysates using NFKB p100 antibody(1:1000 diluted).

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