Estrogen Receptor alpha Recombinant Rabbit mAb - diagbio | 戴格生物

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Estrogen Receptor alpha Recombinant Rabbit mAb

db12490

Product Name : Estrogen Receptor alpha Recombinant Rabbit mAb

Cat.No.: db12490

Synonyms : ER; ESR; Era; ESRA; ESTRR; NR3A1

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Immunogen A synthetic peptide of human Estrogen Receptor alpha
Gene ID 2099
Swiss Prot P03372
Synonyms ER; ESR; Era; ESRA; ESTRR; NR3A1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:100-1:10000
ICC/IF: 1:200
FC: 1:1000
IP: 1:50
Calculated MW 66 kDa
Observed MW 66 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Estrogen Receptor alpha in K562,Hela cell lysates using Estrogen Receptor alpha antibody(1:1000 diluted).

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