TLR2 Recombinant Rabbit mAb - diagbio | 戴格生物

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TLR2 Recombinant Rabbit mAb

db12461

Product Name : TLR2 Recombinant Rabbit mAb

Cat.No.: db12461

Synonyms : TIL4; CD282

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human TLR2
Gene ID 7097
Swiss Prot O60603
Synonyms TIL4; CD282
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:50
Calculated MW 90 kDa
Observed MW 90 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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