STAT5b Recombinant Rabbit mAb - diagbio | 戴格生物

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STAT5b Recombinant Rabbit mAb

db12203

Product Name : STAT5b Recombinant Rabbit mAb

Cat.No.: db12203

Synonyms : STAT5

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human STAT5b
Gene ID 6777
Swiss Prot P51692
Synonyms STAT5
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000
IHC: 1:200
ICC/IF: 1:100
FC: 1:40
IP: 1:40
Calculated MW 90 kDa
Observed MW 90 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of STAT5b in Hela,A549,HL-60 using STAT5b antibody(1:1000 diluted)

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