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STAT5b (DGR32852) Rabbit mAb
db12203
Datasheet
- Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
- Immunogen Recombinant protein of human STAT5b
-
Gene ID
6777
-
Swiss Prot
P51692
- Synonyms STAT5
- Reactivity Human,Mouse,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:200-1:500
ICC/IF: 1:100
FC: 1:20-1:50
IP: 1:20-1:50 - Calculated MW 90 kDa
- Observed MW 90 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR32852
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of STAT5b in Hela,A549,HL-60 using STAT5b antibody(1:1000 diluted) -
Immunohistochemical analysis of paraffin-embedded human breast cancer using db12203 antibody. -
Immunofluorescent analysis of HeLa cells using db12203 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
