Hsp27 Recombinant Rabbit mAb - diagbio | 戴格生物

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Hsp27 Recombinant Rabbit mAb

db12147

Product Name : Hsp27 Recombinant Rabbit mAb

Cat.No.: db12147

Synonyms : CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human Hsp27
Gene ID 3315
Swiss Prot P04792
Synonyms CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Calculated MW 23 kDa
Observed MW 27 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Hsp27 in K562 cell lysates using Hsp27 antibody(1:1000 diluted).
Western blot analysis of extracts from HepG2 cells using db12147 at 1:3000.

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