BackgroundThis gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding
Ser63 of human c-Jun
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of Phospho-c-Jun (Ser63) in K562,C6,3T3 cell lysates using Phospho-c-Jun (Ser63) antibody(1:1000 diluted).
Western blot analysis of extracts from Rat heart tissue using db12132 at 1:1000.
Immunohistochemical analysis of paraffin-embedded human breast cancer using db12132 antibody.