Phospho-STAT1 (Ser727) Recombinant Rabbit mAb - diagbio | 戴格生物

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Phospho-STAT1 (Ser727) Recombinant Rabbit mAb

db12128

Product Name : Phospho-STAT1 (Ser727) Recombinant Rabbit mAb

Cat.No.: db12128

Synonyms : CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser727 of human STAT1
Gene ID 6772
Swiss Prot P42224
Synonyms CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:100-1:200
Calculated MW 87 kDa
Observed MW 87 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Phospho-STAT1 (Ser727) in 3T3 cell lysates using Phospho-STAT1 (Ser727) antibody(1:1000 diluted).

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