Prion Protein (DGR16827) Rabbit mAb - diagbio | 戴格生物

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Recombinant DGRmAb^®

Prion Protein (DGR16827) Rabbit mAb

db12127

Datasheet

Product Name : Prion Protein (DGR16827) Rabbit mAb

Cat.No.: db12127

Synonyms : CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C

Application : WB, IHC-P, FC

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Immunogen A synthetic peptide of human Prion protein PrP
Gene ID 5621
Swiss Prot P04156
Synonyms CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C
Reactivity Human,Mouse,Rat
Application WB, IHC-P, FC
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:200-1:500
FC: 1:50-1:100
Calculated MW 28 kDa
Observed MW 28 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. DGR16827
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Immunohistochemical analysis of paraffin-embedded human breast cancer using db12127 antibody.

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