PP1C alpha/beta Recombinant Rabbit mAb - diagbio | 戴格生物

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PP1C alpha/beta Recombinant Rabbit mAb

db12099

Product Name : PP1C alpha/beta Recombinant Rabbit mAb

Cat.No.: db12099

Synonyms : PP1A; PP-1A; PPP1A; PP1alpha

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human PPP1CA+PPP1CB
Gene ID 5499
Swiss Prot P62136
Synonyms PP1A; PP-1A; PPP1A; PP1alpha
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:2000-1:10000
IHC: 1:20
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 38 kDa
Observed MW 38 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of PPP1CA+PPP1CB in K562,Rat Brain cell lysates using PPP1CA+PPP1CB antibody(1:1000 diluted).

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