Integrin alpha V Recombinant Rabbit mAb - diagbio | 戴格生物

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Integrin alpha V Recombinant Rabbit mAb

db12090

Product Name : Integrin alpha V Recombinant Rabbit mAb

Cat.No.: db12090

Synonyms : CD51; MSK8; VNRA; VTNR

Application : WB, FC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Immunogen A synthetic peptide of human Integrin alpha V
Gene ID 3685
Swiss Prot P06756
Synonyms CD51; MSK8; VNRA; VTNR
Reactivity Human, Mouse, Rat
Application WB, FC
Recommended dilution WB: 1:1000
FC: 1:20
Calculated MW 116 kDa
Observed MW 135, 30 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot analysis of extracts from C6 cells using db12090 at 1:1000.
Western blot analysis of extracts from HepG2，C2C12 cells and Rat heart tissue using db12090 at 1:1000.

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