Caspase-3 Recombinant Rabbit mAb - diagbio | 戴格生物

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Caspase-3 Recombinant Rabbit mAb

db12058

Product Name : Caspase-3 Recombinant Rabbit mAb

Cat.No.: db12058

Synonyms : CPP32; SCA-1; CPP32B

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human Caspase-3
Gene ID 836
Swiss Prot P42574
Synonyms CPP32; SCA-1; CPP32B
Reactivity Human
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:200-1:500
FC: 1:200-1:500
IP: 1:20
Calculated MW 32 kDa
Observed MW 32,17 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Caspase-3 in K562,Hela cell lysates using Caspase-3 antibody(1:1000 diluted).

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