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Caspase-3 (DGR13170) Rabbit mAb
db12058
Datasheet
- Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
- Immunogen A synthetic peptide of human Caspase-3
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Gene ID
836
-
Swiss Prot
P42574
- Synonyms CPP32; SCA-1; CPP32B
- Reactivity Human
- Application WB, IHC, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000-1:5000
IHC: 1:20-1:100
ICC/IF: 1:200-1:500
FC: 1:200-1:500
IP: 1:20 - Calculated MW 32 kDa
- Observed MW 32,17 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13170
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Caspase-3 in K562,Hela cell lysates using Caspase-3 antibody(1:1000 diluted). -
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using db12058 antibody. -
Immunofluorescent analysis of 293 cells using db12058 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
