BackgroundThis gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of KDM1/LSD1 in Hela,CHO-K1,C6,Jurkat cell lysates using KDM1/LSD1 antibody(1:500 diluted).
Western blot analysis of extracts from HepG2,RAW264.7 cells using db12048 at 1:1000.
Immunofluorescent analysis of HeLa cells using db12048 antibody (green), and DAPI (blue).