BackgroundThe protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Storage/StabilityStore at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Western blot detection of GAP43 in Rat Brain lysates using GAP43 antibody(1:1000 diluted).
Immunohistochemical analysis of paraffin-embedded human Brain using db12045 antibody.
Immunofluorescent analysis of SH-SY5Y cells using db12045 antibody (green), and DAPI (blue).