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MCM7 (DGR17001) Rabbit mAb
db11990
Datasheet
- Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Immunogen A synthetic peptide of human MCM7
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Gene ID
4176
-
Swiss Prot
P33993
- Synonyms MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
- Reactivity Human,Rat
- Application WB, IHC-P, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000
IHC-P: 1:50
ICC/IF: 1:50
FC: 1:20
IP: 1:20 - Calculated MW 81 kDa
- Observed MW 81 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR17001
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of MCM7 in K562,C6,Hela cell lysates using MCM7 antibody(1:1000 diluted). -
Western blot analysis of extracts from HCT116 cells using db11990 at 1:2000. -
Immunohistochemical analysis of paraffin-embedded human tonsil using db11990 antibody.
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
