Integrin alpha 5 Recombinant Rabbit mAb - diagbio | 戴格生物

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Integrin alpha 5 Recombinant Rabbit mAb

db11971

Product Name : Integrin alpha 5 Recombinant Rabbit mAb

Cat.No.: db11971

Synonyms : FNRA; CD49e; VLA-5; VLA5A

Application : WB, IHC, ICC/IF, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Immunogen A synthetic peptide of human Integrin alpha 5
Gene ID 3678
Swiss Prot P08648
Synonyms FNRA; CD49e; VLA-5; VLA5A
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC: 1:200-1;500
ICC/IF: 1:50
FC: 1:20
IP: 1:20
Calculated MW 115 kDa
Observed MW 150, 19 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of Integrin alpha 5 in K562,3T3 cell lysates using Integrin alpha 5 antibody(1:1000 diluted).
Western blot analysis of extracts from Rat heart，Mouse kidney tissue using db11971 at 1:3000.

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