HDAC1 Recombinant Rabbit mAb - diagbio | 戴格生物

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HDAC1 Recombinant Rabbit mAb

db11944

Datasheet

Product Name : HDAC1 Recombinant Rabbit mAb

Cat.No.: db11944

Synonyms : HD1; RPD3; GON-10; RPD3L1

Application : WB, IHC-P, ICC/IF, FC, IP

Reactivity : Human,Mouse,Rat

Host species : Rabbit

Background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human HDAC1
Gene ID 3065
Swiss Prot Q13547
Synonyms HD1; RPD3; GON-10; RPD3L1
Reactivity Human,Mouse,Rat
Application WB, IHC-P, ICC/IF, FC, IP
Recommended dilution WB: 1:1000-1:5000
IHC-P: 1:50-1:100
ICC/IF: 1:50
FC: 1:20-1:50
IP: 1:20-1:50
Calculated MW 55 kDa
Observed MW 62 kDa
Host species Rabbit
Clonality Monoclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Western blot detection of HDAC1 in K562 cell lysates using HDAC1 antibody(1:1000 diluted).
Immunofluorescent analysis of Jurkat cells using db11944 antibody (green), and DAPI (blue).

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