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Phospho-ATF2 (Thr71) (DGR13508) Rabbit mAb
db11934
Datasheet
- Background This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
- Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2
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Gene ID
1386
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Swiss Prot
P15336
- Synonyms HB16; CREB2; TREB7; CREB-2; CRE-BP1
- Reactivity Human,Mouse
- Application WB, ICC/IF, IP
-
Recommended dilution
WB: 1:1000-1:5000
ICC/IF: 1:200-1:500
IP: 1:20-1:50 - Calculated MW 55 kDa
- Observed MW 70 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. DGR13508
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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Western blot detection of Phospho-ATF2 (Thr71) in 3T3,Hela cell lysates using Phospho-ATF2 (Thr71) antibody(1:1000 diluted). -
Immunofluorescent analysis of U87-MG cells using db11934 antibody (green), and DAPI (blue).
订购信息
- Package Price (RMB)
- 20μL 698
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
